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UID:20120216wcsn.txt
DTSTART:20120224T150000Z
DTEND:20120224T160000Z
DTSTAMP:20120216T163456Z
SUMMARY:Neuroscience Network Seminar - Dr. S. Hannila\, Feb. 24\, 2012
LOCATION:PX236/238 PsychHealth Centre\, Bannatyne Campus
ORGANIZER;CN=the MNN Office:MAILTO:mnn@sbrc.ca
URL:http://www.scrc.umanitoba.ca/news/?id+20120216wcsn.txt
DESCRIPTION:  The Winnipeg Chapter Society for Neuroscience is pleased to 
 announce this upcoming\n  Manitoba Neuroscience Network Seminar...\n\n  D
 ate:  Friday\, February 24\, 2012\n  Time:  9:00 AM - 10:00 AM\n  Locatio
 n:  PX236/238 PsychHealth Centre\, Bannatyne Campus\n\n  Dr. Sari Hannila
 \n  Assistant Professor\, Department of Human Anatomy & Cell Sciences\,\n
   University of Manitoba\n\n  Topic: Downregulation of Smad2 by secretory
  leukocyte protease inhibitor enhances axonal regeneration in the CNS.\n
 \nBiosketch:  Dr. Hannila is originally from Sudbury\, Ontario\, and rece
 ived her\nBachelor of Science degree in Life Sciences from Queen's Univer
 sity in 1999.\nShe then completed her PhD in the Department of Anatomy an
 d Cell Biology at\nQueen's under the supervision of Dr. Michael Kawaja.  
 Prior to joining the\nUniversity of Manitoba in July\, 2010\, Dr. Hannila
  worked as a postdoctoral\nfellow in the laboratory of Dr. Marie T. Filbi
 n at Hunter College in New York\nCity.\n\nHer research focuses on the neu
 robiology of developing and regenerating axons\nin the central nervous sy
 stem\, with a particular interest in spinal cord\ninjury.  When the spina
 l cord is injured\, regeneration of damaged axons is\ninhibited by CNS my
 elin and this leads to permanent paralysis. During her\npostdoctoral fell
 owship\, Dr. Hannila discovered that a protein called\nsecretory leukocyt
 e protease inhibitor (SLPI) can reverse the inhibitory\neffects of myelin
  and enhance axonal growth.  She is now building on these\nfindings as an
  independent researcher at the University of Manitoba.  She is\ncurrently
  testing SLPI in a rat model of spinal cord injury to determine if\nSLPI 
 can promote axonal regeneration and improve functional recovery.  If SLPI
 \nproves to be effective\, she plans to conduct further studies in which 
 SLPI\nwill be administered in more complex\, clinically-relevant models o
 f spinal\ncord injury.  In addition to its pro-regenerative effects\, SLP
 I also has\nneuroprotective properties and to diversify her research prog
 ram\, Dr. Hannila\nplans to test SLPI in models of neurodegenerative dise
 ases such as multiple\nsclerosis\, amyotrophic lateral sclerosis\, Alzhei
 mer's\, and Parkinson's\ndisease. These studies will be complemented by o
 ngoing experiments that will\ninvestigate the molecular mechanisms underl
 ying SLPI's effects on axonal\ngrowth and neuronal survival\, and this wo
 rk will focus on SLPI's ability to\nregulate gene and protein expression.
 \n\n  Please see the attached notice and post in your area to advertise.
 \n\n  For more information\, contact the MNN Office at\n  (T) 235.3939 or
  email: mnn@sbrc.ca\n\n  Presented in co-operation with University of Man
 itoba Clinical Neuroscience Rounds\n  An initiative of the Winnipeg Chapt
 er Society for Neuroscience\n\nSee attachment: http://www.scrc.umanitoba.
 ca/news/attach/MNN_Hannila_Feb24_2012.pdf
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